---
id: "claim:assessing-the-multimodal-tradeoff-2023-04-18-biorxiv:a91276ca67dc3505cf5b"
kind: "claim"
title: "At intragenic SNPs with strong cell-type-wide ATAC strand preference, gene expression was strongly allele specific."
description: ""
url: "https://sina.bio/claim/at-intragenic-snps-with-strong-cell-type-wide-atac-strand-preference-ge-74748af1"
---

# At intragenic SNPs with strong cell-type-wide ATAC strand preference, gene expression was strongly allele specific.

## Content

At intragenic SNPs with strong cell-type-wide ATAC strand preference, gene expression was strongly allele specific.

## Metadata

```json
{
  "claim_position": 105,
  "source_publication_id": "version:assessing-the-multimodal-tradeoff--2023-04-18-biorxiv",
  "source_work_id": "work:assessing-the-multimodal-tradeoff"
}
```

## Connections (2)

### Assessing the multimodal tradeoff

- ID: `version:assessing-the-multimodal-tradeoff--2023-04-18-biorxiv`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/assessing-the-multimodal-tradeoff>

This publication contains this grounded claim.

> At SNPs inside genes, where ATAC reads indicated a strong strand preference across cell type, gene expression was strongly allele specific in concordance with the open chromatin strand (see Methods, Figure 4a).

Source: 2023-04-18-biorxiv.pdf — <https://sina.bio/source/2023-04-18-biorxiv-pdf>

### At heterozygous intragenic SNPs, allele-specific gene expression is concordant with strand-specific open chromatin when

- ID: `result:assessing-the-multimodal-tradeoff-2023-04-18-biorxiv:d16a531f495c6169a173`
- Kind: `result`
- Direction: `incoming`
- URL: <https://sina.bio/result/at-heterozygous-intragenic-snps-allele-specific-gene-expression-is-conc-2828b4e1>

This claim supports this result.