---
id: "claim:isoform-cell-type-specificity-in-the-mouse-primary-motor-cortex-2021-10-06-nature:0743577b02a585b09270"
kind: "claim"
title: "Full-length transcript coverage allows SMART-seq to quantify isoforms and detect cell-type isoform markers unavailable t"
description: "Full-length transcript coverage allows SMART-seq to quantify isoforms and detect cell-type isoform markers unavailable to 3-prime-end technologies."
url: "https://sina.bio/claim/full-length-transcript-coverage-allows-smart-seq-to-quantify-isoforms-a-687cd28b"
---

# Full-length transcript coverage allows SMART-seq to quantify isoforms and detect cell-type isoform markers unavailable t

Full-length transcript coverage allows SMART-seq to quantify isoforms and detect cell-type isoform markers unavailable to 3-prime-end technologies.

## Content

Full-length transcript coverage allows SMART-seq to quantify isoforms and detect cell-type isoform markers unavailable to 3-prime-end technologies.

## Metadata

```json
{
  "claim_position": 25,
  "source_publication_id": "version:isoform-cell-type-specificity-in-the-mouse-primary-motor-cortex--2021-10-06-nature",
  "source_work_id": "work:isoform-cell-type-specificity-in-the-mouse-primary-motor-cortex"
}
```

## Connections (2)

### Isoform cell-type specificity in the mouse primary motor cortex

- ID: `version:isoform-cell-type-specificity-in-the-mouse-primary-motor-cortex--2021-10-06-nature`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/isoform-cell-type-specificity-in-the-mouse-primary-motor-cortex>

This publication contains this grounded claim.

> However,while SMART-seqhaslowerthroughputthansomeothertechnologies,ithas anotableadvantage:becauseitprobestranscriptsacrosstheirentire length,SMART-seqmakespossibleisoformquantificationandthe detectionofisoformmarkersforcelltypesthatcannotbedetected with3′-endtechnologies(ExtendedDataFigs.

Source: 2021-10-06-nature.pdf — <https://sina.bio/source/2021-10-06-nature-pdf-85dfd458>

### 10x Genomics and SMART-seq equivalently defined broad cell classes, while their different coverage identified complement

- ID: `result:isoform-cell-type-specificity-in-the-mouse-primary-motor-cortex-2021-10-06-nature:b955fde04984362a57e0`
- Kind: `result`
- Direction: `incoming`
- URL: <https://sina.bio/result/10x-genomics-and-smart-seq-equivalently-defined-broad-cell-classes-whil-375f2d6b>

This claim supports this result.