---
id: "claim:massively-scaled-up-testing-for-sars-cov-2-rna-via-next-generation-sequencing-o-b8e8889e79:1be62e3c729eb97287bf"
kind: "claim"
title: "A sample with only standard reads is called SARS-CoV-2 negative."
description: ""
url: "https://sina.bio/claim/a-sample-with-only-standard-reads-is-called-sars-cov-2-negative"
---

# A sample with only standard reads is called SARS-CoV-2 negative.

## Content

A sample with only standard reads is called SARS-CoV-2 negative.

## Metadata

```json
{
  "claim_position": 24,
  "source_publication_id": "version:massively-scaled-up-testing-for-sars-cov-2-rna-via-next-generation-sequencing-of-pooled-and-barcoded-nasal-and-saliva-samples--2021-07-01-nature-biomedical-engineering",
  "source_work_id": "work:massively-scaled-up-testing-for-sars-cov-2-rna-via-next-generation-sequencing-of-pooled-and-barcoded-nasal-and-saliva-samples"
}
```

## Connections (2)

### Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples

- ID: `version:massively-scaled-up-testing-for-sars-cov-2-rna-via-next-generation-sequencing-of-pooled-and-barcoded-nasal-and-saliva-samples--2021-07-01-nature-biomedical-engineering`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/massively-scaled-up-testing-for-sars-cov-2-rna-via-next-generation-sequ-8c628baf>

This publication contains this grounded claim.

> As every sample contains the synthetic RNA,
> SwabSeq controls for the failure of amplification—samples with no
> SARS-CoV-2 detected are those in which only in vitro viral stan-
> dard reads are observed, while those without viral or in vitro viral
> standard reads are inconclusive.

Source: 2021-07-01-nature-biomedical-engineering.pdf — <https://sina.bio/source/2021-07-01-nature-biomedical-engineering-pdf>

### Endpoint PCR with synthetic standards supports ratio-based viral calling while overcoming inhibition and enabling unnorm

- ID: `result:massively-scaled-up-testing-for-sars-cov-2-rna-via-next-generation-sequencing-o-b8e8889e79:56fdcab21fd6ab4d659a`
- Kind: `result`
- Direction: `incoming`
- URL: <https://sina.bio/result/endpoint-pcr-with-synthetic-standards-supports-ratio-based-viral-callin-5cd88476>

This claim supports this result.