---
id: "claim:normalization-for-sampled-count-data-2026-06-22-biorxiv-v4:92d146f78eea7b1b4ba2"
kind: "claim"
title: "Depth normalization before the logarithm changes the effective raw-count pseudocount to cell depth divided by shifted-lo"
description: "Depth normalization before the logarithm changes the effective raw-count pseudocount to cell depth divided by shifted-log scale."
url: "https://sina.bio/claim/depth-normalization-before-the-logarithm-changes-the-effective-raw-coun-6a90bb78"
---

# Depth normalization before the logarithm changes the effective raw-count pseudocount to cell depth divided by shifted-lo

Depth normalization before the logarithm changes the effective raw-count pseudocount to cell depth divided by shifted-log scale.

## Content

Depth normalization before the logarithm changes the effective raw-count pseudocount to cell depth divided by shifted-log scale.

## Metadata

```json
{
  "claim_position": 46,
  "source_publication_id": "version:normalization-for-sampled-count-data--2026-06-22-biorxiv-v4",
  "source_work_id": "work:normalization-for-sampled-count-data"
}
```

## Connections (1)

### Normalization for sampled count data

- ID: `version:normalization-for-sampled-count-data--2026-06-22-biorxiv-v4`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/normalization-for-sampled-count-data>

This publication contains this grounded claim.

> so depth-normalizing before the logarithm has a simple inter- pretation: it changes the effective raw-count pseudocount to 𝑠𝑐/𝐾𝑐.

Source: 2026-06-22-biorxiv-v4.pdf — <https://sina.bio/source/2026-06-22-biorxiv-v4-pdf>