---
id: "claim:normalization-of-single-cell-rna-seq-counts-by-log-x-1-or-log-1-x-2021-03-02-bi-f6d7002293:6a482c52b8e8ec59fdb2"
kind: "claim"
title: "Log transformation during count normalization is a common source of mistakes in reported ACE2 expression."
description: ""
url: "https://sina.bio/claim/log-transformation-during-count-normalization-is-a-common-source-of-mis-7635b725"
---

# Log transformation during count normalization is a common source of mistakes in reported ACE2 expression.

## Content

Log transformation during count normalization is a common source of mistakes in reported ACE2 expression.

## Metadata

```json
{
  "claim_position": 22,
  "source_publication_id": "version:normalization-of-single-cell-rna-seq-counts-by-log-x-1-or-log-1-x--2021-03-02-bioinformatics",
  "source_work_id": "work:normalization-of-single-cell-rna-seq-counts-by-log-x-1-or-log-1-x"
}
```

## Connections (1)

### Normalization of single-cell RNA-seq counts by log (x+ 1) or log (1+ x)

- ID: `version:normalization-of-single-cell-rna-seq-counts-by-log-x-1-or-log-1-x--2021-03-02-bioinformatics`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/normalization-of-single-cell-rna-seq-counts-by-log-x-1-or-log-1-x-a5fd6f46>

This publication contains this grounded claim.

> Another mistake that we've found to be common in reporting ACE2 expression has to do with the log transformation, frequently used as part of a normalization of counts.

Source: 2021-03-02-bioinformatics.pdf — <https://sina.bio/source/2021-03-02-bioinformatics-pdf>