---
id: "claim:quantifying-orthogonal-barcodes-for-sequence-census-assays-2022-10-10-biorxiv:c096345090e1938235c5"
kind: "claim"
title: "Barcode-based sequence census assays use custom or random oligonucleotide sequences to label biological features."
description: ""
url: "https://sina.bio/claim/barcode-based-sequence-census-assays-use-custom-or-random-oligonucleoti-8e45e32e"
---

# Barcode-based sequence census assays use custom or random oligonucleotide sequences to label biological features.

## Content

Barcode-based sequence census assays use custom or random oligonucleotide sequences to label biological features.

## Metadata

```json
{
  "claim_position": 43,
  "source_publication_id": "version:quantifying-orthogonal-barcodes-for-sequence-census-assays--2022-10-10-biorxiv",
  "source_work_id": "work:quantifying-orthogonal-barcodes-for-sequence-census-assays"
}
```

## Connections (1)

### Quantifying orthogonal barcodes for sequence census assays

- ID: `version:quantifying-orthogonal-barcodes-for-sequence-census-assays--2022-10-10-biorxiv`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/quantifying-orthogonal-barcodes-for-sequence-census-assays-cc9d35e3>

This publication contains this grounded claim.

> Barcode-based sequence census assays utilize custom or random oligonucloetide sequences to label various biological features, such as cell-surface proteins or CRISPR perturbations. These assays all rely on barcode quantification, a task that is complicated by barcode design and technical noise. We introduce a modular approach to quantifying barcodes that achieves speed and memory improvements over existing tools. We also introduce a set of quality control metrics, and accompanying tool, for validating barcode designs.

Source: 2022-10-10-biorxiv.pdf — <https://sina.bio/source/2022-10-10-biorxiv-pdf>