---
id: "claim:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-c9bd0e4584:6cf851d8f6fbeee3bce6"
kind: "claim"
title: "Donors differ according to multiple factors, including genetic sequence; between-donor differences could limit our abili"
description: "Donors differ according to multiple factors, including genetic sequence; between-donor differences could limit our ability to identify additional transcriptomic phenotypes distinguishing adipose-resident cell populations and subpopulations.However,arobustnumberofnucleiwascapturedfromeachtissuesample,potentiallymitigating the impact of sample variance, thus allowing us to identify new subpopulations of adipocytes."
url: "https://sina.bio/claim/donors-differ-according-to-multiple-factors-including-genetic-sequence-d5d544d9"
---

# Donors differ according to multiple factors, including genetic sequence; between-donor differences could limit our abili

Donors differ according to multiple factors, including genetic sequence; between-donor differences could limit our ability to identify additional transcriptomic phenotypes distinguishing adipose-resident cell populations and subpopulations.However,arobustnumberofnucleiwascapturedfromeachtissuesample,potentiallymitigating the impact of sample variance, thus allowing us to identify new subpopulations of adipocytes.

## Content

Donors differ according to multiple factors, including genetic sequence; between-donor differences could limit our ability to identify additional transcriptomic phenotypes distinguishing adipose-resident cell populations and subpopulations.However,arobustnumberofnucleiwascapturedfromeachtissuesample,potentiallymitigating the impact of sample variance, thus allowing us to identify new subpopulations of adipocytes.

## Metadata

```json
{
  "claim_position": 219,
  "source_publication_id": "version:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-with-distinct-metabolic-profiles--2025-09-16-biorxiv",
  "source_work_id": "work:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-with-distinct-metabolic-profiles"
}
```

## Connections (1)

### Single-Nucleus Analysis of Human White Adipose Tissue Reveals Adipocyte Subsets with Distinct Metabolic Profiles

- ID: `version:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-with-distinct-metabolic-profiles--2025-09-16-biorxiv`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-201b7737>

This publication contains this grounded claim.

> Donors differ according to multiple factors, including genetic sequence; between-donor differences could limit our ability to identify additional transcriptomic phenotypes distinguishing adipose-resident cell populations and subpopulations.However,arobustnumberofnucleiwascapturedfromeachtissuesample,potentiallymitigating the impact of sample variance, thus allowing us to identify new subpopulations of adipocytes.

Source: 2025-09-16-biorxiv.pdf — <https://sina.bio/source/2025-09-16-biorxiv-pdf>