---
id: "claim:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-c9bd0e4584:f8e20b48eea0e7c9641f"
kind: "claim"
title: "Identification of APC subtypes with distinct adipogenic and inflammatory patterns and anatomical location Using unsuperv"
description: "Identification of APC subtypes with distinct adipogenic and inflammatory patterns and anatomical location Using unsupervised clustering, we identified three distinct adipogenic progenitor cell (APC) populations, termed APC1 (cluster 2), APC2 (cluster 3), and APC3 (cluster 14) (Figure 1C and S2A), all marked by expression of PDGFRA (Figure1D)."
url: "https://sina.bio/claim/identification-of-apc-subtypes-with-distinct-adipogenic-and-inflammator-a0a5d53d"
---

# Identification of APC subtypes with distinct adipogenic and inflammatory patterns and anatomical location Using unsuperv

Identification of APC subtypes with distinct adipogenic and inflammatory patterns and anatomical location Using unsupervised clustering, we identified three distinct adipogenic progenitor cell (APC) populations, termed APC1 (cluster 2), APC2 (cluster 3), and APC3 (cluster 14) (Figure 1C and S2A), all marked by expression of PDGFRA (Figure1D).

## Content

Identification of APC subtypes with distinct adipogenic and inflammatory patterns and anatomical location Using unsupervised clustering, we identified three distinct adipogenic progenitor cell (APC) populations, termed APC1 (cluster 2), APC2 (cluster 3), and APC3 (cluster 14) (Figure 1C and S2A), all marked by expression of PDGFRA (Figure1D).

## Metadata

```json
{
  "claim_position": 53,
  "source_publication_id": "version:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-with-distinct-metabolic-profiles--2025-09-16-biorxiv",
  "source_work_id": "work:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-with-distinct-metabolic-profiles"
}
```

## Connections (2)

### Single-Nucleus Analysis of Human White Adipose Tissue Reveals Adipocyte Subsets with Distinct Metabolic Profiles

- ID: `version:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-with-distinct-metabolic-profiles--2025-09-16-biorxiv`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-201b7737>

This publication contains this grounded claim.

> Identification of APC subtypes with distinct adipogenic and inflammatory patterns and anatomical location Using unsupervised clustering, we identified three distinct adipogenic progenitor cell (APC) populations, termed APC1 (cluster 2), APC2 (cluster 3), and APC3 (cluster 14) (Figure 1C and S2A), all marked by expression of PDGFRA (Figure1D).

Source: 2025-09-16-biorxiv.pdf — <https://sina.bio/source/2025-09-16-biorxiv-pdf>

### Three adipogenic progenitor populations had distinct inflammatory and adipogenic programs: APC1 was inflammatory, APC2 w

- ID: `result:single-nucleus-analysis-of-human-white-adipose-tissue-reveals-adipocyte-subsets-c9bd0e4584:769e6c39475c33646c00`
- Kind: `result`
- Direction: `incoming`
- URL: <https://sina.bio/result/three-adipogenic-progenitor-populations-had-distinct-inflammatory-and-a-570c3990>

This claim supports this result.
