---
id: "claim:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-der-cacfaced0c:870a2e6b37a1038a2220"
kind: "claim"
title: "Given that the majority of immune cells exhibited genotype-specific clustering, along with prior studies in CC founder s"
description: "Given that the majority of immune cells exhibited genotype-specific clustering, along with prior studies in CC founder strains showing differences in immune cell composition in blood, suchasvaryingproportionsofTcells, NKcells, anddendritic cells76, we conducted a pan-tissue immune-focused analy- sis."
url: "https://sina.bio/claim/given-that-the-majority-of-immune-cells-exhibited-genotype-specific-clu-ee90cc65"
---

# Given that the majority of immune cells exhibited genotype-specific clustering, along with prior studies in CC founder s

Given that the majority of immune cells exhibited genotype-specific clustering, along with prior studies in CC founder strains showing differences in immune cell composition in blood, suchasvaryingproportionsofTcells, NKcells, anddendritic cells76, we conducted a pan-tissue immune-focused analy- sis.

## Content

Given that the majority of immune cells exhibited genotype-specific clustering, along with prior studies in CC founder strains showing differences in immune cell composition in blood, suchasvaryingproportionsofTcells, NKcells, anddendritic cells76, we conducted a pan-tissue immune-focused analy- sis.

## Metadata

```json
{
  "claim_position": 99,
  "source_publication_id": "version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2026-04-cell-genomics",
  "source_work_id": "work:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation"
}
```

## Connections (2)

### Common Heritable Immunological Variations Revealed in Genetically Diverse Inbred Mouse Strains of the Collaborative Cross

- ID: `publication:doi:10.4049/jimmunol.1801247`
- Kind: `publication`
- Direction: `outgoing`
- URL: <https://sina.bio/publication/common-heritable-immunological-variations-revealed-in-genetically-diver-88c0e8c2>

This publication is cited in support of this claim.

> Pan-tissue analysis of immune cells: Inflammation
> signature in NZO Kupffer cells
> Given that the majority of immune cells exhibited genotype-spe-
> cific clustering, along with prior studies in CC founder strains
> showing differences in immune cell composition in blood,70
> we
> conducted a pan-tissue immune-focused analysis.

Source: 2026-04-cell-genomics.pdf — <https://sina.bio/source/2026-04-cell-genomics-pdf>

### Systematic cell-type resolved transcriptomes of 8 tissues in 8 lab and wild-derived mouse strains capture global and local expression variation

- ID: `version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2026-04-cell-genomics`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-02081d03>

This publication contains this grounded claim.

> Pan-tissue analysis of immune cells: Inflammation signature in NZO Kupffer cells Given that the majority of immune cells exhibited genotype-spe- cific clustering, along with prior studies in CC founder strains showing differences in immune cell composition in blood,70 we conducted a pan-tissue immune-focused analysis.

Source: 2026-04-cell-genomics.pdf — <https://sina.bio/source/2026-04-cell-genomics-pdf>
