---
id: "claim:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-der-cacfaced0c:b685c56645b43d931c7c"
kind: "claim"
title: "Differential expression analysis was performed for all 28 pairwise genotype comparisons using PyDESeq2145 on non-normali"
description: "Differential expression analysis was performed for all 28 pairwise genotype comparisons using PyDESeq2145 on non-normalized pseudobulk counts per sample, with sex included as a covariate in non-gonadal tissues."
url: "https://sina.bio/claim/differential-expression-analysis-was-performed-for-all-28-pairwise-geno-6b378281"
---

# Differential expression analysis was performed for all 28 pairwise genotype comparisons using PyDESeq2145 on non-normali

Differential expression analysis was performed for all 28 pairwise genotype comparisons using PyDESeq2145 on non-normalized pseudobulk counts per sample, with sex included as a covariate in non-gonadal tissues.

## Content

Differential expression analysis was performed for all 28 pairwise genotype comparisons using PyDESeq2145 on non-normalized pseudobulk counts per sample, with sex included as a covariate in non-gonadal tissues.

## Metadata

```json
{
  "claim_position": 262,
  "source_publication_id": "version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2026-04-cell-genomics",
  "source_work_id": "work:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation"
}
```

## Connections (1)

### Systematic cell-type resolved transcriptomes of 8 tissues in 8 lab and wild-derived mouse strains capture global and local expression variation

- ID: `version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2026-04-cell-genomics`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-02081d03>

This publication contains this grounded claim.

> Differential expression analysis was performed for all 28 pairwise genotype comparisons using a two-sided Wald test via PyDESeq2135 on non-normalized pseudobulk counts per sample, with sex included as a covariate in non- gonadal tissues.

Source: 2026-04-cell-genomics.pdf — <https://sina.bio/source/2026-04-cell-genomics-pdf>