---
id: "claim:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-der-da55913a59:32af7e6fb48015dfda0e"
kind: "claim"
title: "Analyzing gene weights associated with these topics identified Pax7 as highly specific to AJ-depleted topics 4, 5, and 1"
description: "Analyzing gene weights associated with these topics identified Pax7 as highly specific to AJ-depleted topics 4, 5, and 1, while Mef2c and Mir133a-1 are strongly associated with AJ-enriched topics 2 and 7 (Supp Fig. 8d)."
url: "https://sina.bio/claim/analyzing-gene-weights-associated-with-these-topics-identified-pax7-as-21d8ac0d"
---

# Analyzing gene weights associated with these topics identified Pax7 as highly specific to AJ-depleted topics 4, 5, and 1

Analyzing gene weights associated with these topics identified Pax7 as highly specific to AJ-depleted topics 4, 5, and 1, while Mef2c and Mir133a-1 are strongly associated with AJ-enriched topics 2 and 7 (Supp Fig. 8d).

## Content

Analyzing gene weights associated with these topics identified Pax7 as highly specific to AJ-depleted topics 4, 5, and 1, while Mef2c and Mir133a-1 are strongly associated with AJ-enriched topics 2 and 7 (Supp Fig. 8d).

## Metadata

```json
{
  "claim_position": 312,
  "source_publication_id": "version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2025-04-24-biorxiv",
  "source_work_id": "work:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation"
}
```

## Connections (2)

### Systematic cell-type resolved transcriptomes of 8 tissues in 8 lab and wild-derived mouse strains capture global and local expression variation

- ID: `version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2025-04-24-biorxiv`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-3aa7ebaa>

This publication contains this grounded claim.

> Analyzing gene weights associated with these topics identified Pax7 as highly specific to AJ-depleted topics 4, 5, and 1, while Mef2c and Mir133a-1 are strongly associated with AJ-enriched topics 2 and 7 (Supp Fig. 8d).

Source: 2025-04-24-biorxiv.pdf — <https://sina.bio/source/2025-04-24-biorxiv-pdf>

### AJ satellite cells were enriched for regulatory topics 2, 7, 8, and 9, with Mef2c and Mir133a-1 associated with enriched

- ID: `result:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-der-da55913a59:078e661dd3175126b4a2`
- Kind: `result`
- Direction: `incoming`
- URL: <https://sina.bio/result/aj-satellite-cells-were-enriched-for-regulatory-topics-2-7-8-and-9-with-93f5ddf7>

This claim supports this result.