--- id: "claim:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-der-da55913a59:57f07d85e41c086be71a" kind: "claim" title: "Cwc22 is the only protein-coding gene within this region, and amongst the founder strains its expression is uniquely amp" description: "Cwc22 is the only protein-coding gene within this region, and amongst the founder strains its expression is uniquely amplified in WSB60." url: "https://sina.bio/claim/cwc22-is-the-only-protein-coding-gene-within-this-region-and-amongst-th-38a4f302" --- # Cwc22 is the only protein-coding gene within this region, and amongst the founder strains its expression is uniquely amp Cwc22 is the only protein-coding gene within this region, and amongst the founder strains its expression is uniquely amplified in WSB60. ## Content Cwc22 is the only protein-coding gene within this region, and amongst the founder strains its expression is uniquely amplified in WSB60. ## Metadata ```json { "claim_position": 109, "source_publication_id": "version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2025-04-24-biorxiv", "source_work_id": "work:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation" } ``` ## Connections (3) ### R2d2 and Hyperdrive Mechanisms (in Mouse Meiosis) - ID: `publication:doi:10.1371/journal.pgen.1004950` - Kind: `publication` - Direction: `outgoing` - URL: This publication is cited in support of this claim. > Cwc22 is the only protein-coding gene within this region, and amongst the founder strains its expression is uniquely amplified in WSB60. Source: 2025-04-24-biorxiv.pdf — ### Systematic cell-type resolved transcriptomes of 8 tissues in 8 lab and wild-derived mouse strains capture global and local expression variation - ID: `version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2025-04-24-biorxiv` - Kind: `publication` - Direction: `incoming` - URL: This publication contains this grounded claim. > Cwc22 is the only protein-coding gene within this region, and amongst the founder strains its expression is uniquely amplified in WSB60. Source: 2025-04-24-biorxiv.pdf — ### WSB uniquely overexpressed Cwc22 because of copy-number expansion at the R2d2 locus, where Cwc22 is the only protein-cod - ID: `result:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-der-da55913a59:fb6cb18668d941a2a7da` - Kind: `result` - Direction: `incoming` - URL: This claim supports this result.