---
id: "claim:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-der-da55913a59:c376cbb197b40c27dfb1"
kind: "claim"
title: "In Kupffer cells (KCs), we identified cluster 8 as an NZO-specific inflamed state."
description: ""
url: "https://sina.bio/claim/in-kupffer-cells-kcs-we-identified-cluster-8-as-an-nzo-specific-inflame-bd13ee14"
---

# In Kupffer cells (KCs), we identified cluster 8 as an NZO-specific inflamed state.

## Content

In Kupffer cells (KCs), we identified cluster 8 as an NZO-specific inflamed state.

## Metadata

```json
{
  "claim_position": 205,
  "source_publication_id": "version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2025-04-24-biorxiv",
  "source_work_id": "work:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation"
}
```

## Connections (2)

### Systematic cell-type resolved transcriptomes of 8 tissues in 8 lab and wild-derived mouse strains capture global and local expression variation

- ID: `version:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-derived-mouse-strains-capture-global-and-local-expression-variation--2025-04-24-biorxiv`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-3aa7ebaa>

This publication contains this grounded claim.

> In Kupffer cells (KCs), we identified cluster 8 as an NZO-specific inflamed state.

Source: 2025-04-24-biorxiv.pdf — <https://sina.bio/source/2025-04-24-biorxiv-pdf>

### An inflammatory Kupffer-cell state comprised 86% of NZO Kupffer cells, was enriched for innate immunity, phagocytosis, a

- ID: `result:systematic-cell-type-resolved-transcriptomes-of-8-tissues-in-8-lab-and-wild-der-da55913a59:50a13a83552c967f0261`
- Kind: `result`
- Direction: `incoming`
- URL: <https://sina.bio/result/an-inflammatory-kupffer-cell-state-comprised-86-of-nzo-kupffer-cells-wa-67d6ad8c>

This claim supports this result.