---
id: "claim:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis-3717bd8a9e:54459d3c62430286b086"
kind: "claim"
title: "Analogous Scanpy marker filtering raised per-cluster marker overlap from 0.22 to 0.92."
description: ""
url: "https://sina.bio/claim/analogous-scanpy-marker-filtering-raised-per-cluster-marker-overlap-fro-1abf14ac"
---

# Analogous Scanpy marker filtering raised per-cluster marker overlap from 0.22 to 0.92.

## Content

Analogous Scanpy marker filtering raised per-cluster marker overlap from 0.22 to 0.92.

## Metadata

```json
{
  "claim_position": 32,
  "source_publication_id": "version:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis--2026-04-cell-systems",
  "source_work_id": "work:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis"
}
```

## Connections (2)

### The impact of package selection and versioning on single-cell RNA-seq analysis

- ID: `version:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis--2026-04-cell-systems`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-a-dae7bb70>

This publication contains this grounded claim.

> Applying analogous threshold
> ing to Scanpy vastly reduces the problem, increasing the Jac
> card index from 0.22 to 0.92

Source: 2026-04-cell-systems.pdf — <https://sina.bio/source/2026-04-cell-systems-pdf>

### Default significant-marker sets have Jaccard overlap 0.62 and Seurat reports about 50% more markers, but matching differ

- ID: `result:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis-3717bd8a9e:588a106994cd8512d694`
- Kind: `result`
- Direction: `incoming`
- URL: <https://sina.bio/result/default-significant-marker-sets-have-jaccard-overlap-0-62-and-seurat-re-d7749a0a>

This claim supports this result.