---
id: "claim:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis-3717bd8a9e:92e2f430aa73e169ea32"
kind: "claim"
title: "Default adjusted-p-value Spearman correlation was 0.848 and aligned Seurat-like arguments nearly eliminated differences."
description: ""
url: "https://sina.bio/claim/default-adjusted-p-value-spearman-correlation-was-0-848-and-aligned-seu-1a205244"
---

# Default adjusted-p-value Spearman correlation was 0.848 and aligned Seurat-like arguments nearly eliminated differences.

## Content

Default adjusted-p-value Spearman correlation was 0.848 and aligned Seurat-like arguments nearly eliminated differences.

## Metadata

```json
{
  "claim_position": 36,
  "source_publication_id": "version:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis--2026-04-cell-systems",
  "source_work_id": "work:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis"
}
```

## Connections (2)

### The impact of package selection and versioning on single-cell RNA-seq analysis

- ID: `version:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis--2026-04-cell-systems`
- Kind: `publication`
- Direction: `incoming`
- URL: <https://sina.bio/publication/the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-a-dae7bb70>

This publication contains this grounded claim.

> The Spearman correlation of adjusted p
> values between Seurat and Scanpy was 0.848

Source: 2026-04-cell-systems.pdf — <https://sina.bio/source/2026-04-cell-systems-pdf>

> When function arguments were aligned to be like
> Seurat, virtually all differences in adjusted p value disappeared

Source: 2026-04-cell-systems.pdf — <https://sina.bio/source/2026-04-cell-systems-pdf>

### Default packages produce extreme log-fold-change discrepancies and adjusted-p-value threshold flips, while aligning Seur

- ID: `result:the-impact-of-package-selection-and-versioning-on-single-cell-rna-seq-analysis-3717bd8a9e:f1cb1aa1aa59e1a3a248`
- Kind: `result`
- Direction: `incoming`
- URL: <https://sina.bio/result/default-packages-produce-extreme-log-fold-change-discrepancies-and-adju-4a50411e>

This claim supports this result.
