Modular, efficient and constant-memory single-cell RNA-seq preprocessing

Single-cell RNA-seq preprocessing quantifies transcript or gene abundance in individual cells. Experiments can span 10^6 to 10^10 reads, while existing workflows can require extensive time and disk space or memory that grows with dataset size. kallisto-bustools achieves near-optimal speed, constant memory, scaling to arbitrarily large datasets, Cell Ranger-consistent downstream analyses, and fast RNA-velocity analysis.